Description

Barbital-D5 is a deuterated analog of barbital, a barbiturate derivative, where five hydrogen atoms are replaced with deuterium, a stable isotope of hydrogen. This isotopic labeling is critical for applications requiring internal standards in quantitative mass spectrometry, ensuring high analytical accuracy and reproducibility. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, forensic, and clinical diagnostics sectors who require precise measurement of barbiturate compounds.

Application

• Used as an internal standard for the accurate quantification of barbital and related barbiturates in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) analysis.
• Essential in pharmaceutical research and development for pharmacokinetic studies, metabolic profiling, and drug metabolism investigations.
• Applied in forensic toxicology for the definitive identification and measurement of barbiturates in biological samples.
• Supports clinical diagnostics in developing and validating assays for therapeutic drug monitoring.
• Facilitates doping control analysis in sports to detect the misuse of prohibited substances.
• Utilized in environmental analysis for tracing pharmaceutical pollutants.
• Enables chemical synthesis research as a labeled starting material or tracer to study reaction mechanisms.

Basic Information

Product Name	Barbital-D5
CAS No.	1189694-78-7
Molecular Formula	C8D5H7N2O3
Molecular Weight	189.21 g/mol
Synonyms	5,5-Diethylbarbituric Acid-d5; Barbitone-d5; Veronal-d5; Diethylmalonylurea-d5; 5,5-Diethyl-2,4,6(1H,3H,5H)-pyrimidinetrione-d5; Diethylbarbituric Acid-d5; Malonal-d5
EINECS	Contact for details

Quality Control

Every batch of Barbital-D5 CAS NO 1189694-78-7 is manufactured and analyzed under strict quality management protocols. We guarantee high chemical purity and isotopic enrichment, typically ≥98% (chemical purity) and ≥99% atom D, confirmed by advanced analytical techniques including NMR and MS. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and solvent content is provided with each shipment to ensure traceability and compliance with your research or quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 99.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.