Description

Biotin-Peg3-Ch2Cooh CAS NO 1189560-96-0 is a heterobifunctional polyethylene glycol (PEG) linker featuring a biotin group for affinity purification and a carboxylic acid terminus for conjugation to amine-containing molecules. This compound is critical for creating stable, site-specific bioconjugates with enhanced solubility and reduced immunogenicity. It is primarily needed by researchers and manufacturers in the fields of bioconjugation, targeted drug delivery, and diagnostic assay development.

Application

• Conjugation reagent for attaching biotin tags to antibodies, peptides, and proteins for use in immunoassays (ELISA, Western Blot).
• Key intermediate in the synthesis of Antibody-Drug Conjugates (ADCs) and other targeted biotherapeutics.
• Functionalization of nanoparticles and surfaces for biosensor and diagnostic device development.
• Preparation of affinity chromatography resins and solid supports for protein purification.
• Tool compound in chemical biology for studying protein-protein interactions and cellular trafficking.
• Modification of oligonucleotides and other biomolecules to introduce a biotin handle for detection or capture.

Basic Information

Product Name	Biotin-Peg3-Ch2Cooh
CAS No.	1189560-96-0
Molecular Formula	C24H42N4O9S
Molecular Weight	562.68 g/mol
Synonyms	Biotin-PEG3-acid; Biotin-PEG3-CH2COOH; Biotin-PEG3-Propionic Acid; 2-[2-[2-[2-(5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoylamino)ethoxy]ethoxy]ethoxy]acetic Acid; Biotin-amide-PEG3-C2-acid; Biotin-PEG3-C2-acid; Biotin-triethylene glycol-acetic acid; Biotin-PEG3-CA
EINECS	Contact for details

Quality Control

Our Biotin-Peg3-Ch2Cooh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.