Description

R- n-Methyl-[1,1'-Binaphthalene]-2,2'-Diamine CAS NO 1187857-13-1 is a chiral, axially di-substituted binaphthyl derivative of significant interest in asymmetric synthesis. Its value lies in its utility as a sophisticated ligand or building block for constructing complex molecular architectures with high enantioselectivity. This compound is primarily needed by research and development chemists in the pharmaceutical and advanced materials sectors, where precise stereochemical control is paramount for developing new active ingredients and functional molecules.

Application

• As a chiral ligand or catalyst precursor in asymmetric hydrogenation and carbon-carbon bond-forming reactions.
• As a key intermediate in the synthesis of novel pharmaceuticals, particularly those targeting central nervous system disorders.
• In the development of chiral stationary phases (CSPs) for analytical and preparative-scale chromatographic separation of enantiomers.
• As a building block for constructing chiral macrocycles or molecular tweezers with host-guest chemistry applications.
• In materials science for the synthesis of chiral polymers or small molecules with potential in nonlinear optics (NLO).
• For academic and industrial research into new methodologies for atropisomer-selective synthesis.

Basic Information

Item	Detail
Product Name	R- n-Methyl-[1,1'-Binaphthalene]-2,2'-Diamine
CAS No.	1187857-13-1
Molecular Formula	C21H18N2
Molecular Weight	298.38 g/mol
Synonyms	(R)-N-Methyl-1,1'-binaphthalene-2,2'-diamine; (R)-N-Methyl-BINAM; (R)-2,2'-Diamino-1,1'-binaphthyl N-methyl derivative; (R)-Methyl-BINAM; (R)-1,1'-Binaphthalene-2,2'-diamine, N-methyl-; (R)-N-Methyl-2,2'-diamino-1,1'-binaphthyl; (R)-MNBA; (R)-N-Methyl-2,2'-diamino-1,1'-binaphthyl
EINECS	Contact for details

Quality Control

Our R- n-Methyl-[1,1'-Binaphthalene]-2,2'-Diamine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for research and process development. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.