Description

1,3-Dimethyluric Acid-13C4,15N3 is a high-purity, stable isotope-labeled analog of 1,3-dimethyluric acid, a key metabolite in the study of caffeine and xanthine metabolism. This compound is essential for providing unmatched accuracy and reliability in quantitative mass spectrometry-based analyses, serving as an ideal internal standard. It is primarily utilized by research scientists and quality control laboratories in the pharmaceutical, clinical diagnostics, and nutritional biochemistry sectors.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of 1,3-dimethyluric acid and related purine metabolites in biological matrices like plasma, serum, and urine.
• Pharmacokinetic and Metabolic Studies: Enables accurate tracking of caffeine metabolism and disposition in drug development and clinical research.
• Clinical Diagnostic Assays: Used in the development and validation of high-sensitivity tests for inborn errors of metabolism and liver function.
• Nutritional and Sports Science Research: Facilitates studies on caffeine intake, metabolism, and ergogenic effects in human subjects.
• Biomarker Discovery and Validation: Supports proteomic and metabolomic research aiming to identify new biomarkers related to purine metabolism.
• Quality Control & Method Development: Serves as a reference material in analytical laboratories to ensure method accuracy, precision, and compliance.

Basic Information

Item	Detail
Product Name	1,3-Dimethyluric Acid-13C4,15N3
CAS No.	1173019-16-3
Molecular Formula	C713C4H10N15N3O3
Molecular Weight	Contact for details
Synonyms	1,3-Dimethyluric Acid-13C4,15N3; 1,3-Dimethyl-13C4,15N3-uric Acid; 1,3-Dimethyl-2,6,8(1H,3H,9H)-purinetrione-13C4,15N3; 8-Oxo-1,3-dimethyl-13C4,15N3-xanthine; 1,3-Dimethyl-13C4,15N3-2,6,8-trihydroxypurine; Isotopically Labeled 1,3-DMU; [13C4,15N3]-1,3-Dimethyluric Acid
EINECS	Contact for details

Quality Control

Every batch of 1,3-Dimethyluric Acid-13C4,15N3 is manufactured and analyzed under strict quality systems to ensure the highest isotopic and chemical purity for research and diagnostic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing isotopic enrichment, chemical purity, and analytical methods (NMR, HPLC, MS) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98%
Isotopic Enrichment	≥ 99 atom % 13C; ≥ 99 atom % 15N
Chemical Purity	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.