Description

Ste-Glu-Aeea-Aeea-Osu CAS NO 1169630-40-3 is a specialized heterobifunctional crosslinking reagent featuring an activated ester (OSu) and a protected thiol-reactive group. This compound is engineered for the precise, site-specific conjugation of biomolecules, enabling the creation of stable, well-defined constructs. It is an essential tool for researchers and developers in the fields of bioconjugation, antibody-drug conjugate (ADC) development, and advanced therapeutic modalities.

Application

• Antibody-Drug Conjugate (ADC) Linker Chemistry: For the controlled attachment of cytotoxic payloads to monoclonal antibodies via lysine residues.
• Protein and Peptide Labeling: Site-specific introduction of fluorophores, biotin, or other probes for diagnostic assays and imaging.
• Surface Functionalization: Modification of nanoparticles, biosensors, or chromatographic media with bioactive ligands.
• Polymer-Protein Hybrids: Synthesis of PEGylated proteins or other polymer-conjugated biologics to enhance pharmacokinetic properties.
• Immobilization Matrices: Creating affinity chromatography supports by coupling proteins or peptides to solid phases.
• Diagnostic Reagent Development: Building components for immunoassays and biosensors requiring stable covalent linkages.

Basic Information

Product Name	Ste-Glu-Aeea-Aeea-Osu
CAS No.	1169630-40-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-Succinimidyl Stearoyl-Glu-AEEA-AEEA ester; Stearoyl-Glu-AEEA-AEEA-OSu; Heterobifunctional PEG linker; Lipidic PEG crosslinker; NHS ester of Ste-Glu-(PEG)2; AEEA-AEEA based linker; N-hydroxysuccinimide ester linker
EINECS	Contact for details

Quality Control

Our Ste-Glu-Aeea-Aeea-Osu is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive bioconjugation applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.