Description

2-(Pyrrolidinomethyl)Phenylboronic Acid, Pinacol Ester is a sophisticated, nitrogen-containing boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in the dual functionality provided by the protected boronic acid group and the pyrrolidine moiety, enabling complex coupling reactions and serving as a precursor for advanced pharmaceutical intermediates. This compound is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: As a key electrophile or nucleophile for constructing biaryl and heterobiaryl scaffolds central to drug discovery.
• Pharmaceutical Intermediate: Synthesis of complex molecules targeting neurological disorders, oncology, and other therapeutic areas.
• Agrochemical Research: Development of novel herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science & OLED Development: Building block for creating organic semiconductors, ligands for catalysts, and emissive layer materials.
• Chemical Biology & Probe Development: Used in creating molecular probes for studying enzyme activity and biological pathways.
• Library Synthesis for High-Throughput Screening: Enables the rapid generation of diverse compound libraries in medicinal chemistry programs.

Basic Information

Product Name	2-(Pyrrolidinomethyl)Phenylboronic Acid, Pinacol Ester
CAS No.	1150271-49-0
Molecular Formula	C₁₇H₂₆BNO₂
Molecular Weight	287.21 g/mol
Synonyms	2-(Pyrrolidin-1-ylmethyl)phenylboronic acid pinacol ester; [2-(Pyrrolidin-1-ylmethyl)phenyl]boronic acid pinacol ester; 2-(1-Pyrrolidinylmethyl)benzeneboronic acid pinacol ester; B-[2-(Pyrrolidin-1-ylmethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 2-(Pyrrolidinomethyl)benzeneboronic acid pinacol ester; 1-Pyrrolidine, 1-[[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl]-
EINECS	Contact for details

Quality Control

Our 2-(Pyrrolidinomethyl)Phenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.