Description

n-Iodoacetylglucosamine Tetraacetate is a key chemical intermediate used for the site-specific labeling and modification of biomolecules. This compound is valued for its role in advanced biochemical research and development, particularly in the study of carbohydrate-protein interactions and cellular processes. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in glycobiology, proteomics, and drug discovery.

Application

• Glycoprotein Engineering: Acts as a crucial reagent for the chemoenzymatic synthesis and site-specific labeling of glycoproteins.
• Bioconjugation: Used for the covalent attachment of probes, tags, or drugs to biomolecules via thiol-reactive iodoacetyl chemistry.
• Metabolic Oligosaccharide Engineering (MOE): Serves as a precursor or tool compound for tagging and visualizing cell-surface glycans.
• Enzyme Activity Studies: Employed in the development of assays to study glycosyltransferase or glycosidase enzyme activity and inhibition.
• Antibody-Drug Conjugate (ADC) Research: Facilitates the development of novel linker-payload systems for targeted cancer therapies.
• Diagnostic Reagent Development: Used in the creation of sensitive detection kits and biosensors for carbohydrate-related biomarkers.

Basic Information

Product Name	n-Iodoacetylglucosamine Tetraacetate
CAS No.	1141846-81-2
Molecular Formula	C16H22INO11
Molecular Weight	531.25 g/mol
Synonyms	1,3,4,6-Tetra-O-acetyl-2-deoxy-2-[(iodoacetyl)amino]-β-D-glucopyranose; N-Iodoacetylglucosamine tetraacetate; 2-Deoxy-2-[(iodoacetyl)amino]-D-glucopyranose 1,3,4,6-tetraacetate; GlcNAc(Iodoacetyl)-tetraacetate; Iodoacetamido-glucosamine tetraacetate; N-(Iodoacetyl)-β-D-glucosamine tetraacetate; 2-(Iodoacetamido)-2-deoxy-1,3,4,6-tetra-O-acetyl-β-D-glucopyranose
EINECS	Contact for details

Quality Control

Our n-Iodoacetylglucosamine Tetraacetate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to guarantee the reliability of our supply for critical biochemical workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.