Description

Ac-Iepd-Afc CAS NO 1135417-31-0 is a specialized, high-purity chemical building block used in advanced research and development. This compound is critical for the synthesis of novel pharmaceutical intermediates and complex organic molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical, biotechnology, and fine chemical industries for drug discovery and process optimization.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs.
• Peptide Mimetics Research: Used in the design and development of peptidomimetics and constrained peptides for therapeutic applications.
• Protease Inhibitor Development: Serves as a core scaffold or building block for creating inhibitors targeting specific protease enzymes.
• Bioconjugation: Employed in the site-specific modification of proteins, antibodies, or other biomolecules for drug delivery and diagnostics.
• Chemical Biology Probes: Integral for constructing activity-based probes (ABPs) to study enzyme function and mechanism in biological systems.
• Fine Chemical Synthesis: Used in multi-step organic synthesis to introduce specific functional groups or chiral centers.

Basic Information

Product Name	Ac-Iepd-Afc
CAS No.	1135417-31-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ac-Ile-Glu(OBzl)-Pro-Asp(OBzl)-AFC; Ac-Ile-Glu(OBzl)-Pro-Asp(OBzl)-7-Amino-4-trifluoromethylcoumarin; Ac-IEPD-AFC; Ac-Ile-Glu(OBzl)-Pro-Asp(OBzl)-AFC Substrate; Caspase-8 Substrate I, Ac-IEPD-AFC; Fluorogenic Caspase-8 Substrate
EINECS	Contact for details

Quality Control

Our Ac-Iepd-Afc is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to equilibrate to room temperature before opening to prevent condensation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.