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N6-Benzoyl-Cyclic Amp (Sodium Salt) CAS NO 1135306-29-4


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CAS No.:1135306-29-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

N6-Benzoyl-Cyclic Amp (Sodium Salt) is a chemically modified, cell-permeable derivative of cyclic adenosine monophosphate (cAMP), designed for enhanced stability and targeted biological activity. This compound matters as a potent and selective activator of protein kinase A (PKA), serving as a crucial research tool for studying intracellular signaling pathways. It is primarily needed by researchers and developers in the fields of biochemical research, pharmaceutical development, and cell biology for investigating cAMP-mediated processes.

Application

  • Biochemical Research: As a potent and cell-permeable PKA activator for studying cAMP-dependent signal transduction pathways in vitro and in cell-based assays.
  • Pharmaceutical R&D: Used as a reference standard and a key intermediate in the discovery and development of novel therapeutics targeting PKA-related disorders.
  • Cell Biology Studies: For investigating the role of cAMP in cellular functions such as metabolism, gene expression, and ion channel regulation.
  • Enzyme Kinetics: Employed in enzymatic assays to study PKA kinetics, inhibition, and activation mechanisms.
  • Neuroscience Research: To explore the effects of cAMP modulation on neuronal signaling, synaptic plasticity, and memory formation.
  • Cardiovascular Research: For examining the role of PKA in heart muscle contraction, vascular tone, and other cardiac functions.

Basic Information

Product Name N6-Benzoyl-Cyclic Amp (Sodium Salt)
CAS No. 1135306-29-4
Molecular Formula C₁₇H₁₈N₅NaO₇P
Molecular Weight 473.32 g/mol
Synonyms N6-Benzoyl-cAMP sodium salt; N6-Benzoyladenosine 3',5'-cyclic monophosphate sodium salt; 6-Benzoylaminopurine cyclic monophosphate sodium salt; N6-Bz-cAMP Na; Bz-cAMP sodium salt; N6-Benzoyl-cyclic adenosine monophosphate sodium salt; cAMP, N6-benzoyl-, sodium salt
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Quality Control

Our N6-Benzoyl-Cyclic Amp (Sodium Salt) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Heavy Metals ≤ 20 ppm
Residual Solvents (GC) Meets ICH guidelines
Biological Activity Tested in standard PKA activation assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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