Description

n-Biotinyl D-Erythro-Sphingosine-1-Phosphate is a high-purity, biotin-conjugated derivative of the key bioactive lipid sphingosine-1-phosphate (S1P). This specialized compound is engineered for advanced biochemical research, offering a powerful tool for the detection, isolation, and study of S1P-binding proteins and receptors. It is essential for researchers in pharmaceutical discovery and life sciences, particularly those focused on lipid signaling, immunology, and cancer biology. The product is supplied with guaranteed quality to ensure reliable and reproducible experimental results.

Application

• Biochemical Research Probe: Used as a critical tool for studying S1P receptor (S1PR) signaling pathways, internalization, and trafficking.
• Affinity Purification: Enables the isolation and identification of S1P-binding proteins from complex biological samples via streptavidin-biotin interaction.
• Drug Discovery & Screening: Serves as a key reagent in high-throughput screening (HTS) assays to identify novel agonists or antagonists of the S1P receptor family.
• Immunology Studies: Facilitates research into the role of S1P in lymphocyte egress, vascular integrity, and inflammatory responses.
• Cell Signaling Analysis: Employed in pull-down assays and western blotting to investigate downstream signaling events mediated by S1P.
• Diagnostic Development: Acts as a capture molecule in the development of diagnostic assays targeting S1P pathway biomarkers.

Basic Information

Item	Details
Product Name	n-Biotinyl D-Erythro-Sphingosine-1-Phosphate
CAS No.	1093733-24-4
Molecular Formula	C34H62N4O8PS
Molecular Weight	717.92 g/mol
Synonyms	Biotin-S1P; Biotinylated Sphingosine-1-Phosphate; D-erythro-Sphingosine-1-phosphate biotin conjugate; N-Biotinyl-D-erythro-sphingosine-1-phosphate; Biotin-Sphingosine 1-Phosphate; S1P-Biotin; Biotin conjugate of Sphingosine-1-Phosphate; (2S,3R,4E)-2-Amino-3-hydroxy-4-octadecen-1-yl Dihydrogen Phosphate Biotinyl Derivative
EINECS	Contact for details

Quality Control

Our n-Biotinyl D-Erythro-Sphingosine-1-Phosphate is manufactured under strict quality management systems to ensure the highest standards of purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment, mass spectrometry (MS) for identity confirmation, and NMR for structural verification. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support research and development with products that meet the stringent requirements of pharmaceutical and advanced life science applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, Ethanol; Slightly soluble in aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.