Description

1-Palmitoyl-2-Cholesterylcarbonoyl-Sn-Glycero-3-Phosphocholine is a high-purity synthetic phospholipid derivative, specifically engineered for advanced research and formulation applications. This compound is valued for its unique structural combination of a saturated fatty acid chain and a cholesterol moiety, which imparts specific biophysical properties to lipid membranes. It is primarily utilized by researchers and product developers in the pharmaceutical and biotechnology sectors. Its precise synthesis ensures consistent performance in critical applications.

Application

• Liposome and Nanoparticle Formulation: A key component for creating stable, targeted drug delivery systems, particularly for hydrophobic or amphiphilic active ingredients.
• Membrane Biophysics Research: Used as a model lipid to study membrane fluidity, phase behavior, and cholesterol-lipid interactions in artificial bilayer systems.
• Biomimetic Coatings: Employed in the development of surface coatings that mimic natural cell membranes for biosensor and implantable device applications.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in lipidomics and pharmaceutical analysis.
• Cell Culture & Transfection Reagents: A potential excipient in specialized cell culture media or as a component in novel lipid-based transfection agents.

Basic Information

Product Name	1-Palmitoyl-2-Cholesterylcarbonoyl-Sn-Glycero-3-Phosphocholine
CAS No.	1085528-78-4
Molecular Formula	C57H104NO8P
Molecular Weight	962.42 g/mol
Synonyms	Cholesterol-PC; 16:0 Cholesterol PC; 1-Palmitoyl-2-cholesterylhemisuccinoyl-sn-glycero-3-phosphocholine; Cholesterol-hemisuccinoyl phosphatidylcholine; Palmitoyl Cholesterol Phosphatidylcholine; Chol-PC; Phosphatidylcholine, 1-palmitoyl-2-(3-((3b)-cholest-5-en-3-yloxy)-3-oxopropanoyl)-; Lipoid Chol-PC
EINECS	Contact for details

Quality Control

Every batch of 1-Palmitoyl-2-Cholesterylcarbonoyl-Sn-Glycero-3-Phosphocholine is produced and analyzed under strict quality management protocols. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.