Description

Palmitoyl Aminoethyl Methanethiosulfonate is a specialized thiol-reactive chemical reagent designed for site-specific protein and peptide modification. This compound matters for researchers and manufacturers requiring precise, covalent attachment of palmitoyl groups or other functionalities to cysteine residues, enabling advanced bioconjugation and labeling strategies. It is needed by professionals in pharmaceutical R&D, proteomics, and bioconjugate chemistry for developing targeted therapeutics, diagnostic probes, and studying protein-lipid interactions.

Application

• Bioconjugation Reagent: For the site-specific modification of cysteine-containing proteins and peptides.
• Lipidation Mimetics: Introducing palmitoyl groups to study protein lipidation, membrane anchoring, and trafficking.
• Proteomics Research: As a tool for labeling, affinity purification, or mass spectrometry tagging of thiol groups.
• Antibody-Drug Conjugate (ADC) Development: Enabling controlled payload attachment via engineered cysteine residues.
• Surface Functionalization: Modifying gold nanoparticles or other surfaces via thiol-gold chemistry for biosensor applications.
• Cross-linking Studies: For investigating protein-protein interactions or creating stable protein complexes.

Basic Information

Product Name	Palmitoyl Aminoethyl Methanethiosulfonate
CAS No.	1076199-30-8
Molecular Formula	C21H41NO4S2
Molecular Weight	435.67 g/mol
Synonyms	N-Palmitoyl-S-(2-aminoethyl) methanethiosulfonate; 2-((Palmitoylamino)ethyl) methanethiosulfonate; S-(2-Aminoethyl) N-palmitoyl methanethiosulfonate; Palmitoyl-AE-MTS; MTS-Palm; Thiol-reactive palmitoyl reagent; Protein palmitoylation reagent; Cysteine-specific palmitoylation agent
EINECS	Contact for details

Quality Control

Our Palmitoyl Aminoethyl Methanethiosulfonate is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) in a dry, freezer. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.