Description

Omadacycline (Tosylate) CAS NO 1075240-43-5 is a novel, semi-synthetic aminomethylcycline antibiotic belonging to the tetracycline class. It is valued for its broad-spectrum activity against Gram-positive, Gram-negative, and atypical pathogens, including those resistant to other antibiotic classes. This active pharmaceutical ingredient (API) is primarily required by pharmaceutical manufacturers and research institutions for the development and production of next-generation antibacterial therapies.

Application

• Pharmaceutical API: Core active ingredient in the formulation of oral and intravenous antibacterial drugs.
• Antibacterial Drug Development: Key compound for R&D focused on combating multidrug-resistant bacterial infections.
• Clinical Research: Used in preclinical and clinical studies to evaluate efficacy and safety profiles.
• Reference Standard: Serves as a high-purity standard for analytical testing and quality control in laboratories.
• Combinatorial Therapy Research: Investigated in combination with other agents for enhanced therapeutic outcomes.

Basic Information

Product Name	Omadacycline (Tosylate)
CAS No.	1075240-43-5
Molecular Formula	C₂₉H₄₀N₄O₇S
Molecular Weight	572.72 g/mol
Synonyms	Omadacycline p-Toluenesulfonate; PTK 0796 Tosylate; Amadacycline Tosylate; (4S,4aS,5aR,12aS)-9-[[2-(Aminomethyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinyl]carbonylamino]-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide 4-Methylbenzenesulfonate; NUZYRA (Brand Name API)
EINECS	Contact for details

Quality Control

Our Omadacycline (Tosylate) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods, to ensure compliance with pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and specification adherence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.