Description

(R)-4-[(Tritylthio)Methyl]Oxazolidine-2,5-Dione is a high-value, chiral oxazolidinedione derivative featuring a trityl-protected thiol group. This compound serves as a crucial advanced pharmaceutical intermediate and a versatile chiral building block for the synthesis of complex bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing novel therapeutic agents, particularly in areas requiring stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for CNS and antiviral drugs.
• Peptidomimetic Synthesis: Used in the construction of constrained peptide analogs and protease inhibitors due to its oxazolidinedione scaffold.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor for introducing stereocenters in complex organic synthesis.
• Protecting Group Chemistry: The tritylthio moiety can act as a protective group for thiols in multi-step synthetic sequences.
• Chemical Biology Research: Utilized in the design and synthesis of molecular probes and tool compounds for studying enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs for the production of client-specific, high-value intermediates under cGMP conditions.

Basic Information

Product Name	(R)-4-[(Tritylthio)Methyl]Oxazolidine-2,5-Dione
CAS No.	1051374-19-6
Molecular Formula	C23H19NO3S
Molecular Weight	389.47 g/mol
Synonyms	(R)-4-[(Triphenylmethylthio)methyl]-1,3-oxazolidine-2,5-dione; (R)-4-[(Tritylthio)methyl]-2,5-oxazolidinedione; (4R)-4-[(Triphenylmethylsulfanyl)methyl]-1,3-oxazolidine-2,5-dione; (R)-Tritylthio-methyl-oxazolidinedione; (R)-TTO; (R)-4-(Tritylthiomethyl)oxazolidine-2,5-dione
EINECS	Contact for details

Quality Control

Our (R)-4-[(Tritylthio)Methyl]Oxazolidine-2,5-Dione is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical purity and enantiomeric excess. Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles are provided and available upon request. We support development and commercial projects with specifications tailored to meet cGMP and other relevant regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.