Description

Peg13-Tos CAS NO 1050500-41-8 is a specialized polyethylene glycol (PEG) derivative, specifically a tosylate-activated PEG13 linker. This compound is a critical reagent in bioconjugation and pharmaceutical development, enabling the precise attachment of functional molecules to peptides, proteins, and other biomolecules. It is essential for researchers and manufacturers in the fields of biopharmaceuticals, advanced drug delivery systems, and diagnostic reagent development who require reliable, high-purity linkers for creating stable, functional conjugates.

Application

• Bioconjugation Reagent: Used for the site-specific modification of peptides, proteins, and antibodies to attach drugs, dyes, or other functional groups.
• Pharmaceutical Linker: Serves as a key component in the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutics.
• PEGylation Agent: Employed to PEGylate biomolecules, improving their solubility, stability, and circulation time in vivo.
• Polymer Chemistry Intermediate: Acts as a macro-initiator or functional chain-end for synthesizing block copolymers and functionalized polymers.
• Diagnostic Reagent Synthesis: Utilized in the development of contrast agents and labeled probes for imaging and diagnostic assays.
• Crosslinking Agent: Facilitates the crosslinking of polymers or biomaterials for hydrogel and scaffold fabrication in biomedical engineering.
• Surface Functionalization: Used to modify nanoparticles and solid surfaces with PEG chains to impart stealth properties and biocompatibility.

Basic Information

Item	Detail
Product Name	Peg13-Tos
CAS No.	1050500-41-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PEG13 Tosylate; Poly(ethylene glycol)13 p-toluenesulfonate; α-Methyl-ω-tosyl-poly(ethylene glycol)13; mPEG13-Tosylate; PEG 600 Tosylate (approx.); 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(4-Methylbenzenesulfonyloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol; Tos-PEG13-OH; PEGylated Tosylate Linker
EINECS	Contact for details

Quality Control

Our Peg13-Tos is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and assay, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.