Description

Methyl n-Biotinyl-6-Amino-2-Naphthonate CAS NO 1041143-49-0 is a high-purity, synthetic biochemical reagent that serves as a critical building block and labeling agent. This compound is engineered to combine the biological activity of biotin with a naphthalene-based fluorophore, enabling advanced detection and conjugation applications. It is essential for researchers and manufacturers in the pharmaceutical, diagnostic, and life science sectors who require precise molecular tools for bioconjugation, assay development, and targeted drug delivery systems.

Application

• Bioconjugation Reagent: Used for labeling antibodies, proteins, and peptides with biotin for use in immunoassays (ELISA, Western Blot) and affinity purification systems (streptavidin/avidin).
• Diagnostic Probe Synthesis: A key intermediate in the development of fluorescent and chemiluminescent diagnostic probes and biosensors.
• Pharmaceutical Research: Employed in the synthesis of targeted drug conjugates and in studying drug-receptor interactions via biotin-streptavidin technology.
• Molecular Biology: Facilitates the labeling and detection of nucleic acids (DNA, RNA) in hybridization assays and fluorescence in situ hybridization (FISH).
• Cell Biology & Imaging: Used to tag cell surface receptors and other biomolecules for visualization and tracking in fluorescence microscopy and flow cytometry.
• Material Science: Functionalization of nanoparticles and surfaces for creating bioactive materials and lab-on-a-chip devices.

Basic Information

Product Name	Methyl n-Biotinyl-6-Amino-2-Naphthonate
CAS No.	1041143-49-0
Molecular Formula	C27H33N3O5S
Molecular Weight	511.64 g/mol
Synonyms	Methyl 6-[(5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl)amino]-2-naphthoate; 6-[(Biotinyl)amino]-2-naphthalenecarboxylic acid methyl ester; Biotinyl-6-amino-2-naphthoic acid methyl ester; N-Biotinyl-6-amino-2-naphthoic acid methyl ester; Biotin-6-A-2-NA Methyl Ester; Biotinylated Naphthoate Ester; B-6A2N Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl n-Biotinyl-6-Amino-2-Naphthonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) to ensure traceability and compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.