Description

n-Biotinylcaproylaminocaproylaminoethyl Methanethiosulfonate is a specialized, heterobifunctional crosslinking reagent designed for precise bioconjugation. This compound is engineered to facilitate the site-specific labeling of proteins, peptides, and other biomolecules, enabling advanced research in structural biology and diagnostics. It is an essential tool for scientists and manufacturers in the fields of pharmaceutical development, proteomics, and diagnostic assay production, where controlled and stable linkage between biological entities is required.

Application

• Site-Specific Protein Labeling: For attaching biotin, fluorophores, or other probes to specific cysteine residues in proteins for structural studies.
• Bioconjugation in Diagnostic Kits: Used in the development of ELISA, lateral flow assays, and other immunoassays to create stable antibody-enzyme or antibody-bead conjugates.
• Affinity Chromatography Ligand Immobilization: For coupling biotinylated ligands to thiol-reactive solid supports to create specialized purification columns.
• Surface Plasmon Resonance (SPR) Chip Functionalization: Enables the controlled attachment of biomolecules to sensor surfaces for real-time interaction analysis.
• Proteomics and Crosslinking Mass Spectrometry (XL-MS): Acts as a crosslinker to study protein-protein interactions and map protein structures.
• Nanoparticle and Drug Delivery System Conjugation: For functionalizing liposomes, polymers, or other nanocarriers with targeting ligands.

Basic Information

Product Name	n-Biotinylcaproylaminocaproylaminoethyl Methanethiosulfonate
CAS No.	1038749-81-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Biotin-LC-LC-MTS; Biotin-(LC)2-MTS; Biotin-PEG2-Maleimide (alternative functional group equivalent); N-Biotinyl-6-(6-((2-(methanesulfonothioyl)ethyl)amino)hexanamido)hexanamide; Biotinylated Methanethiosulfonate Reagent; Biotin-LC-SS-MTS; EZ-Link Biotin-MTS; Heterobifunctional Biotin Crosslinker
EINECS	Contact for details

Quality Control

Our n-Biotinylcaproylaminocaproylaminoethyl Methanethiosulfonate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive bioconjugation applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistency for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term stability, store under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.