Description

Bbq-650 n-Hydroxysuccinimide Ester is a specialized, high-purity chemical reagent designed for advanced bioconjugation and labeling applications. This compound is critical for creating stable amide bonds with primary amines, enabling the precise modification of biomolecules such as proteins, peptides, and antibodies. It is an essential tool for researchers and manufacturers in the fields of biopharmaceutical development, diagnostic assay production, and advanced materials science, where reliable and efficient cross-linking is required.

Application

• Bioconjugation Reagent: For the covalent labeling and cross-linking of proteins, antibodies, and peptides with fluorophores, enzymes, or other functional molecules.
• Diagnostic Kit Manufacturing: Used in the development and production of immunoassays (ELISA, lateral flow tests) and biosensors.
• Antibody-Drug Conjugate (ADC) Development: Serves as a key linker chemistry in the synthesis of targeted cancer therapeutics.
• Biomaterial Functionalization: For modifying surfaces of nanoparticles, hydrogels, and polymers to introduce bioactive properties.
• Proteomics Research: Employed in mass spectrometry workflows for labeling and enriching specific protein targets.
• Oligonucleotide Modification: Enables the attachment of reporter groups or other molecules to DNA/RNA probes.

Basic Information

Product Name	Bbq-650 n-Hydroxysuccinimide Ester
CAS No.	1027512-30-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	BBQ-650 NHS ester; BBQ-650 N-hydroxysuccinimide ester; BBQ-650 SE; BBQ-650 Succinimidyl Ester; 6-((7-(Diethylamino)-2-oxo-2H-chromen-4-yl)carbonyl)oxy)-2,5-dioxopyrrolidin-1-yl (E)-3-(4-((E)-2-(7-(diethylamino)-2-oxo-2H-chromen-4-yl)vinyl)phenoxy)propanoate; Bbq-650 fluorescent dye NHS ester
EINECS	Contact for details

Quality Control

Our Bbq-650 NHS Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high performance. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, absorbance/fluorescence properties, and other critical parameters is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term stability, store under inert atmosphere.

Specification

Item	Specification
Appearance	Dark blue or dark green solid/powder
Identification (HPLC/UV-Vis)	Conforms
Purity (HPLC)	≥ 95%
Absorption Max (λmax)	~650 nm
Emission Max (λem)	~670 nm
Extinction Coefficient (ε)	Contact for details
Moisture Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.