Description

tert-Butyl 2-(2,3-Difluoro-6-Nitrophenyl)-3-Oxobutanoate is a high-purity, advanced pharmaceutical intermediate characterized by its specific difluoro-nitrophenyl and oxobutanoate functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily utilized by pharmaceutical manufacturers and R&D laboratories specializing in the development of novel therapeutic agents, where its precise structure serves as a key building block.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in research and development for creating novel molecular entities with potential therapeutic activity.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides, leveraging its fluorinated aromatic structure.
• Organic Synthesis & Process Development: Employed in method development and scale-up processes for fine chemical production.
• Material Science Research: Potential use in the development of specialty polymers or advanced organic materials.

Basic Information

Product Name	tert-Butyl 2-(2,3-Difluoro-6-Nitrophenyl)-3-Oxobutanoate
CAS No.	1022112-25-9
Molecular Formula	C14H15F2NO5
Molecular Weight	315.27 g/mol
Synonyms	2-(2,3-Difluoro-6-nitrophenyl)-3-oxobutanoic acid tert-butyl ester; tert-Butyl 3-oxo-2-(2,3-difluoro-6-nitrophenyl)butanoate; 3-Oxobutanoic acid, 2-(2,3-difluoro-6-nitrophenyl)-, 1,1-dimethylethyl ester; 1022112-25-9; Butanoic acid, 2-(2,3-difluoro-6-nitrophenyl)-3-oxo-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(2,3-Difluoro-6-Nitrophenyl)-3-Oxobutanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong alkalis and incompatible organic solvents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.