Description

Biotin-Peg2-C6-Azide CAS NO 1011268-29-3 is a high-purity, heterobifunctional crosslinking reagent designed for advanced bioconjugation and labeling applications. This compound integrates a biotin affinity tag, a polyethylene glycol (PEG) spacer for solubility, and a terminal azide group for highly specific click chemistry reactions. It is an essential tool for researchers and manufacturers in the life sciences sector who require precise and stable modification of biomolecules, such as proteins, antibodies, and oligonucleotides, for detection, purification, and diagnostic purposes.

Application

• Bioconjugation and Protein Labeling: Site-specific modification of proteins and antibodies with biotin tags for downstream detection using streptavidin systems.
• Proteomics and Biomarker Discovery: Functionalization of surfaces or beads for the capture and enrichment of biotinylated targets in pull-down assays.
• Diagnostic Assay Development: Conjugation to oligonucleotide probes or other molecules for use in ELISA, lateral flow, and other immunoassay platforms.
• Chemical Biology and Drug Discovery: As a key reagent in activity-based protein profiling (ABPP) and target identification studies via click chemistry.
• Nanoparticle and Material Science: Surface functionalization of nanoparticles, polymers, and other materials for targeted delivery and imaging applications.
• ADC (Antibody-Drug Conjugate) Research: Facilitating the development of novel linker-payload constructs in therapeutic antibody research.

Basic Information

Product Name	Biotin-Peg2-C6-Azide
CAS No.	1011268-29-3
Molecular Formula	C26H46N6O6S
Molecular Weight	570.75 g/mol
Synonyms	Biotin-PEG2-C6-Azide; Biotin-(PEG)2-C6-Azide; 6-((6-((2-(5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethoxy)ethoxy)hexyl)azide; Biotin-PEG2-Alkyne Azide; Biotinylated PEG Azide; Azido-PEG2-C6-Biotin; N-(6-Azidohexyl)-N'-(biotinyl-PEG2)-amide; Biotin-PEG2-N3
EINECS	Contact for details

Quality Control

Our Biotin-Peg2-C6-Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, keep the primary container sealed in a secondary protective bag with desiccant.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.