Description

Caged-Ins(145)P3 / Pm is a specialized caged or photolabile compound, identified by CAS No. 1009832-82-9. This product is engineered for advanced research applications where precise, light-triggered release of an active moiety is required. It is a critical reagent for scientists in photochemistry, neurobiology, and cell signaling studies, enabling high-precision temporal control in experimental protocols.

Application

• Photochemical Release Studies: Used as a caged precursor for the light-induced, spatiotemporally controlled release of biologically active molecules in live-cell imaging and physiology experiments.
• Neuroscience Research: Enables the precise uncaging of neurotransmitters or second messengers (e.g., inositol phosphates) to study receptor function and neuronal signaling pathways with millisecond precision.
• Cell Biology & Physiology: A tool for investigating intracellular calcium signaling, enzyme kinetics, and other dynamic cellular processes through flash photolysis techniques.
• Biochemical Probe Development: Serves as a key intermediate or active component in the synthesis of advanced probes for studying phosphoinositide metabolism and related pathways.
• Materials Science (Photosensitive Materials): Potential applications in the development of light-responsive polymers, smart materials, and advanced coatings where controlled release is desired.

Basic Information

Product Name	Caged-Ins(145)P3 / Pm
CAS No.	1009832-82-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Caged Inositol 1,4,5-Trisphosphate; Caged Ins(1,4,5)P3; Photolabile InsP3; 1-(2-Nitrophenyl)ethyl (NPE) caged IP3; DMNP-caged IP3 (potential variant); Light-sensitive IP3 precursor; Photocaged second messenger; P4(1)-[1-(2-nitrophenyl)ethyl] ester of Ins(1,4,5)P3
EINECS	Contact for details

Quality Control

Every batch of Caged-Ins(145)P3 / Pm is produced and analyzed under stringent conditions to ensure the highest standards of purity and performance for research applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA), documenting identity, purity, and photolytic efficiency, is provided with each shipment to guarantee traceability and reproducibility for your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Due to its strictly light-sensitive and hygroscopic nature, this material must be stored in the dark at -20°C or below under desiccant. For long-term stability, store under an inert atmosphere (e.g., argon or nitrogen) in single-use aliquots to minimize freeze-thaw cycles and exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Photolytic Efficiency	≥ 80% release upon irradiation
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, ethanol, aqueous buffer (as specified)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.