Description

(R)-2-Amino-4-Pentenoic Acid T-Butyl Ester is a high-value, non-natural amino acid derivative featuring a chiral center and a reactive terminal alkene group. This compound is a critical chiral building block for the synthesis of complex pharmaceuticals and bioactive molecules, enabling precise stereochemical control. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, peptidomimetics, and other active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with specific stereochemical requirements.
• Peptide Chemistry: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to introduce the (R)-2-amino-4-pentenoic acid moiety.
• Chemical Biology Probes: The alkene handle allows for further functionalization via click chemistry (e.g., thiol-ene reactions) for labeling and bioconjugation.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to construct complex chiral architectures.
• Material Science: Potential monomer for the synthesis of specialized polymers with unique functional properties.

Basic Information

Product Name	(R)-2-Amino-4-Pentenoic Acid T-Butyl Ester
CAS No.	199588-89-1
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	(R)-2-((tert-Butoxycarbonyl)amino)pent-4-enoic Acid; (R)-Boc-4-Pentenylglycine; (R)-N-Boc-2-Amino-4-pentenoic Acid; (R)-2-(tert-Butoxycarbonylamino)-4-pentenoic Acid; (R)-2-Amino-4-pentenoic acid 1,1-dimethylethyl ester; (2R)-2-[[(2-Methylpropan-2-yl)oxycarbonyl]amino]pent-4-enoic Acid; tert-Butyl (R)-2-amino-4-pentenoate
EINECS	Contact for details

Quality Control

Our (R)-2-Amino-4-Pentenoic Acid T-Butyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.