Description

1,2-Dimyristoyl-3-Trimethylammonium-Propane is a synthetic, cationic lipid widely recognized for its role in forming stable liposomes and facilitating nucleic acid delivery. This compound is essential for researchers and manufacturers developing advanced non-viral transfection reagents and lipid nanoparticle (LNP) delivery systems. It is a critical raw material for pharmaceutical R&D, particularly in the formulation of mRNA vaccines, gene therapies, and other cutting-edge biotechnological applications.

Application

• Lipid Nanoparticle (LNP) Formulation: A key cationic lipid component for encapsulating and delivering mRNA, siRNA, and other nucleic acids in therapeutic applications.
• Non-Viral Transfection Reagents: Used in the development of liposome-based transfection agents for introducing genetic material into cells in vitro and in vivo.
• Gene Therapy Research: Serves as a critical building block in creating delivery vectors for gene editing tools (e.g., CRISPR-Cas9) and gene replacement therapies.
• Vaccine Adjuvant Systems: Employed in the design of novel adjuvant systems that enhance immune response by improving antigen presentation.
• Drug Delivery Carriers: Utilized to create targeted liposomal carriers for the delivery of small molecule drugs, improving solubility and bioavailability.
• Biomaterials and Coatings: Can be incorporated into surface coatings to create cationic surfaces for antimicrobial or DNA-binding applications.

Basic Information

Product Name	1,2-Dimyristoyl-3-Trimethylammonium-Propane
CAS No.	197974-74-6
Molecular Formula	C₃₇H₇₄NO₄⁺ (typically as a chloride or other salt)
Molecular Weight	Contact for details
Synonyms	DMTAP; 1,2-Ditetradecanoyl-3-(trimethylammonio)propane; DMTAP Chloride; 1,2-Dimyristoyl-sn-glycero-3-ethylphosphocholine (analog); TAP-14; Cationic lipid 14:0; Trimethyl(2,3-bis(tetradecanoyloxy)propyl)ammonium; CL-14:0
EINECS	Contact for details

Quality Control

Our 1,2-Dimyristoyl-3-Trimethylammonium-Propane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and biotechnology research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep container tightly sealed in a desiccated environment after opening.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.