Description

D-Myo-Inositol, 3,4,5-Tris(Dihydrogen Phosphate) 1-(2R)-2-(5Z,8Z,11Z,14Z)-1-Oxo-5,8,11,14-Eicosatetraenyloxy-3-(1-Oxooctadecyl)Oxypropyl Hydrogen Phosphate is a complex, high-purity phospholipid derivative of inositol phosphate, designed for advanced biochemical and pharmaceutical research. This compound is critical for studying intracellular signaling pathways, particularly those involving phosphoinositide metabolism and lipid second messengers. It serves as a key reference standard and synthetic intermediate for researchers and manufacturers in lipidomics, drug discovery, and the development of novel therapeutic agents targeting metabolic and signaling disorders.

Application

• Biochemical Research: As a critical substrate or inhibitor in enzymatic assays to study phosphatidylinositol kinases, phosphatases, and phospholipases.
• Pharmaceutical R&D: As a high-purity reference standard or synthetic building block for developing novel drugs targeting phosphoinositide 3-kinase (PI3K) pathways, cancer, and inflammatory diseases.
• Lipidomics & Metabolomics: Used as a certified standard for the qualitative and quantitative analysis of complex lipid species in mass spectrometry-based profiling.
• Cell Signaling Studies: Investigation of intracellular signal transduction mechanisms, including those related to cell growth, proliferation, and apoptosis.
• Diagnostic Reagent Development: A key component in the formulation of diagnostic kits and assays for monitoring specific metabolic pathways.
• Academic Research: Fundamental research in biochemistry, molecular biology, and chemical biology to elucidate the role of inositol phosphates and their derivatives.

Basic Information

Product Name	D-Myo-Inositol, 3,4,5-Tris(Dihydrogen Phosphate) 1-(2R)-2-(5Z,8Z,11Z,14Z)-1-Oxo-5,8,11,14-Eicosatetraenyloxy-3-(1-Oxooctadecyl)Oxypropyl Hydrogen Phosphate
CAS No.	194924-60-2
Molecular Formula	C47H84O19P4
Molecular Weight	1081.07 g/mol (Contact for details)
Synonyms	PI(3,4,5)P3 (1,2-Di-O-arachidonyl) Analog; D-myo-Inositol 1,2-Di-O-arachidonyl-3,4,5-trisphosphate; 1,2-Di-O-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-(1-D-myo-inositol 3,4,5-trisphosphate); Phosphatidylinositol (3,4,5)-trisphosphate Diarachidonoyl; PtdIns(3,4,5)P3 (C20:4/C20:4); Inositol 1,2-Diarachidonoyl-3,4,5-trisphosphate; PIP3 (1,2-Diarachidonoyl) Derivative
EINECS	Contact for details

Quality Control

Our D-Myo-Inositol, 3,4,5-Tris(Dihydrogen Phosphate) derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data upon request, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the sealed vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in chloroform/methanol mixtures
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.