Description

1-Deoxysphingosine (M18:1) is a bioactive sphingolipid metabolite, specifically a 1-deoxy derivative of sphingosine. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a biomarker and potential mediator in metabolic and neurological disorders. It is primarily utilized by researchers and developers in the life sciences sector for targeted studies on sphingolipid metabolism, cell signaling pathways, and disease mechanism investigation.

Application

• Biomedical Research: Used as a critical reference standard and analytical tool in studies of sphingolipid biology and related pathologies.
• Drug Discovery & Development: Serves as a key intermediate or target molecule in screening programs for metabolic and neurological diseases.
• Diagnostic Assay Development: Employed in the calibration and validation of LC-MS/MS and other analytical methods for biomarker quantification.
• Cell Biology Studies: Applied in vitro to investigate its effects on cell proliferation, apoptosis, and metabolic stress responses.
• Academic Research: Essential for universities and research institutes exploring novel aspects of lipid signaling and metabolism.

Basic Information

Product Name	1-Deoxysphingosine (M18:1)
CAS No.	193222-34-3
Molecular Formula	C18H37NO2
Molecular Weight	299.50 g/mol
Synonyms	1-Deoxysphinganine; (2S,3R)-2-Amino-3-hydroxyoctadecane; D-erythro-1-Deoxysphinganine; Sa; M18:1; 1-Deoxy-sphinganine; Deoxysphinganine; 1-Desoxysphinganine
EINECS	Contact for details

Quality Control

Our 1-Deoxysphingosine (M18:1) is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and structural confirmation by NMR and MS, to ensure identity, potency, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.