Description

Caspase-5 is a crucial cysteine-aspartic protease enzyme involved in the regulation of apoptosis and inflammatory signaling pathways. Its specific activity makes it an essential research tool for studying programmed cell death mechanisms and developing novel therapeutic strategies. This high-purity biochemical is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on oncology, immunology, and neurodegenerative disease research. Caspase-5 CAS NO 192465-11-5 is supplied with guaranteed activity and stability for reliable experimental results.

Application

• Biochemical Research: Used as a key reagent in enzymatic assays to study caspase activation cascades and apoptosis.
• Drug Discovery & Screening: Employed in high-throughput screening (HTS) platforms to identify and validate novel caspase-5 inhibitors or activators for therapeutic development.
• Cell Biology Studies: Essential for investigating the role of inflammatory caspases in pyroptosis and innate immune responses.
• Diagnostic Development: Serves as a component in developing diagnostic kits for detecting abnormal apoptotic activity.
• Protein Interaction Analysis: Used in studies to understand substrate specificity and protein-protein interactions within the caspase family.
• Academic & Pharmaceutical R&D: A fundamental tool for basic research and pre-clinical development in areas like cancer, autoimmune diseases, and sepsis.

Basic Information

Product Name	Caspase-5
CAS No.	192465-11-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Caspase 5; Caspase-5 Enzyme; Apoptotic Cysteine Protease; ICErel-III; Protease, Caspase-5; Inflammatory Caspase-5; CASP5; EC 3.4.22.-
EINECS	Contact for details

Quality Control

Our Caspase-5 is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and high biological activity. Each lot is characterized for purity, specific activity, and absence of contaminating proteases. A comprehensive Certificate of Analysis (COA) detailing assay results, storage buffer composition, and activity units is provided with every shipment to support your research compliance and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in aliquots to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use. Handle under appropriate laboratory conditions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (Activity)	Conforms
Purity (SDS-PAGE)	≥ 90%
Specific Activity	≥ [Value] units/mg protein
Protein Concentration	Provided on COA
Buffer Composition	Provided on COA
Endotoxin Level	< 1.0 EU/µg (where applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.