Description

2-(2-((tert-Butoxycarbonyl)Amino)Ethoxy)-Ethyl 4-Methylbenzenesulfonate is a specialized chemical intermediate featuring a protected amine group and a reactive tosylate moiety. This compound is critical for researchers and manufacturers requiring precise, high-purity building blocks for complex organic synthesis. It is primarily utilized in the development of pharmaceuticals, advanced materials, and bioactive molecules where controlled functionalization is essential.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring pegylated or spacer-linked amine functionalities.
• Peptide & Protein Conjugation: Used to introduce protected linker arms for the site-specific modification of peptides, proteins, and antibodies in bioconjugation chemistry.
• Polymer & Dendrimer Synthesis: Serves as a functional monomer or cross-linking agent in the preparation of specialized polymers, dendrimers, and smart materials.
• Protecting Group Chemistry: The tert-butoxycarbonyl (Boc) protected amine allows for selective reactions at other sites, with subsequent deprotection under mild acidic conditions.
• Chemical Biology Probes: Employed in the creation of molecular probes, tags, and diagnostic agents for research and diagnostic applications.
• Ligand & Catalyst Development: Useful precursor for synthesizing complex ligands and catalysts used in asymmetric synthesis and catalysis.

Basic Information

Product Name	2-(2-((tert-Butoxycarbonyl)Amino)Ethoxy)-Ethyl 4-Methylbenzenesulfonate
CAS No.	192132-77-7
Molecular Formula	C16H25NO6S
Molecular Weight	359.44 g/mol
Synonyms	Boc-NH-PEG2-Tosylate; 2-[2-[(tert-Butoxycarbonyl)amino]ethoxy]ethyl 4-methylbenzenesulfonate; 2-(2-(Boc-amino)ethoxy)ethyl tosylate; N-Boc-2,2'-(ethylenedioxy)diethylamine 4-toluenesulfonate; tert-Butyl N-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethyl]carbamate; PEG2-Boc-tosylate; Boc-Amino-PEG2-Tos; Boc-PEG2-OTs
EINECS	Contact for details

Quality Control

Our 2-(2-((tert-Butoxycarbonyl)Amino)Ethoxy)-Ethyl 4-Methylbenzenesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.