Description

Kinase (Phosphorylating), Phosphatidylinositol 3-Phosphate 5- is a high-purity biochemical reagent and a key intermediate in the study of intracellular signaling pathways. This compound is essential for researchers and developers investigating the phosphoinositide 3-kinase (PI3K) signaling cascade, a critical regulator of cell growth, proliferation, and survival. It is primarily used in life science research, pharmaceutical development, and as a standard for analytical method validation.

Application

• Biochemical Research: As a substrate or intermediate in enzymatic studies of PI3K and related kinase/phosphatase pathways.
• Pharmaceutical Development: Used in high-throughput screening (HTS) assays to identify and characterize novel PI3K pathway inhibitors for oncology and metabolic disease therapeutics.
• Diagnostic Reagent Manufacturing: Serves as a critical component or standard in the production of diagnostic kits targeting phosphoinositide signaling biomarkers.
• Cell Signaling Studies: Employed in cell-based assays to elucidate the role of specific phosphoinositides in cellular processes like autophagy, membrane trafficking, and cytoskeletal reorganization.
• Analytical Standard: Used as a reference standard in liquid chromatography-mass spectrometry (LC-MS) and other analytical techniques for quantitative analysis of cellular lipids.

Basic Information

Product Name	Kinase (Phosphorylating), Phosphatidylinositol 3-Phosphate 5-
CAS No.	190606-24-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PI(3)P5-kinase substrate; Phosphatidylinositol 3-phosphate 5-kinase substrate; D-myo-Phosphatidylinositol 3-phosphate (PtdIns(3)P); PtdIns3P; 1-Phosphatidyl-1D-myo-inositol 3-phosphate; PI3P; Phosphoinositide PI(3)P
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing parameters such as purity, identity, and impurity profiles. We adhere to GMP principles for the handling of high-value biochemical intermediates to ensure batch-to-batch consistency and reliability for critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Solubility	Soluble in chloroform/methanol mixtures

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.