Description

1,4-Dideoxy-1,4-Epithio-D-Ribitol is a specialized sulfur-containing carbohydrate derivative, serving as a valuable chiral building block and intermediate in advanced organic synthesis. Its unique epithio structure makes it a critical precursor for the development of novel nucleoside analogs and enzyme inhibitors. This high-purity compound is essential for research and development in pharmaceutical chemistry, particularly for antiviral and anticancer drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer therapeutics.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate glycosidase and related enzyme mechanisms.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery projects targeting carbohydrate-processing enzymes.
• Organic Synthesis: Employed as a versatile building block for the preparation of complex, sulfur-functionalized sugars and heterocyclic compounds.
• Glycomics & Glycobiology: Useful as a tool compound for probing biological pathways involving carbohydrate recognition and metabolism.

Basic Information

Product Name	1,4-Dideoxy-1,4-Epithio-D-Ribitol
CAS No.	190315-43-6
Molecular Formula	C5H10O2S
Molecular Weight	134.20 g/mol
Synonyms	1,4-Dideoxy-1,4-epithio-D-ribitol; 1,4-Dideoxy-1,4-epithio-D-ribitol; 1,4-Dideoxy-1,4-epithio-D-ribitol; 1,4-Epithio-1,4-dideoxy-D-ribitol; D-1,4-Dideoxy-1,4-epithioribitol; (2R,3S,4S)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol
EINECS	Contact for details

Quality Control

Our 1,4-Dideoxy-1,4-Epithio-D-Ribitol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation by IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.