Description

Ac-Vdvad-Pna is a synthetic peptide sequence of significant interest in biochemical and pharmaceutical research. This compound serves as a critical building block and a model substrate for studying enzyme kinetics and protease specificity. It is primarily utilized by research institutions and pharmaceutical developers focused on peptide-based drug discovery and proteomics. The product is supplied to the global market with a focus on high purity and batch-to-batch consistency for reliable experimental results.

Application

• Protease Substrate Research: Used as a specific cleavage sequence to study the activity and inhibition of various proteases.
• Biochemical Assay Development: Serves as a key component in developing colorimetric or fluorometric assays for enzyme activity screening.
• Peptide Synthesis Intermediate: Acts as a protected fragment for the solid-phase synthesis of larger, more complex peptide chains.
• Pharmaceutical R&D: Employed in early-stage drug discovery for identifying and optimizing lead compounds that target specific enzymatic pathways.
• Academic Research: Utilized in university laboratories for fundamental studies in biochemistry, molecular biology, and medicinal chemistry.
• Quality Control Standard: Functions as a reference standard for calibrating analytical instruments like HPLC and mass spectrometers in QC labs.

Basic Information

Product Name	Ac-Vdvad-Pna
CAS No.	189684-53-5
Molecular Formula	C31H41N7O9
Molecular Weight	655.71 g/mol
Synonyms	Ac-Val-Asp-Val-Ala-Asp-pNA; Ac-VDVAD-p-Nitroanilide; Caspase-2 Substrate, Ac-VDVAD-pNA; N-Acetyl-Val-Asp-Val-Ala-Asp p-nitroanilide; Ac-VDVAD-PNA; Ac-VDVAD-pNA (Caspase-2 Substrate); Ac-Val-Asp(OMe)-Val-Ala-Asp(OMe)-pNA; N-Acetyl-L-valyl-N-(4-nitroanilido)-L-aspartyl-L-valyl-L-alanyl-L-aspartamide
EINECS	Contact for details

Quality Control

Our Ac-Vdvad-Pna is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 98%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.