Description

n-Hexadecanoyl Coenzyme A Lithium Salt is a high-purity, long-chain acyl-CoA ester essential for studying lipid metabolism and enzyme function. This compound serves as a critical biochemical tool for researchers investigating fatty acid oxidation, lipid biosynthesis, and acyltransferase activity in vitro. It is primarily utilized by biochemists and pharmaceutical researchers in academic, biotechnology, and drug discovery settings for mechanistic studies and high-throughput screening assays.

Application

• Biochemical Research: Substrate for enzymes involved in fatty acid β-oxidation pathways.
• Enzyme Kinetics: Used to determine kinetic parameters (Km, Vmax) of acyl-CoA utilizing enzymes like thioesterases and synthetases.
• Lipidomics & Metabolomics: Serves as a standard or reference compound in mass spectrometry-based lipid analysis.
• Drug Discovery Screening: Key reagent in assays targeting metabolic disorders, such as those related to mitochondrial function.
• In Vitro Diagnostics (IVD): Component in diagnostic kits for measuring specific metabolic enzyme activities.
• Cell Signaling Studies: Investigated for its role in protein acylation and cellular signaling processes.

Basic Information

Product Name	n-Hexadecanoyl Coenzyme A Lithium Salt
CAS No.	188174-64-3
Molecular Formula	C37H64N7O17P3S • xLi
Molecular Weight	~1000.8 g/mol (Free acid, approximate)
Synonyms	Palmitoyl-CoA Lithium Salt; Hexadecanoyl Coenzyme A Lithium Salt; Coenzyme A, S-hexadecanoate, lithium salt; Palmitoyl-Coenzyme A Lithium; C16:0-CoA Li Salt; Palmitoyl-CoA Li+; Pal-CoA Lithium Salt; S-Palmitoyl CoA Lithium
EINECS	Contact for details

Quality Control

Our n-Hexadecanoyl Coenzyme A Lithium Salt is manufactured under controlled conditions to ensure batch-to-batch consistency and high biochemical activity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and stability. We adhere to stringent quality management practices suitable for research and diagnostic applications. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This material is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated at -70°C. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Biological Activity	Assayed via enzymatic conversion

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.