Description

Arachidonic Acid n-Hydroxysuccinimidyl Ester is a chemically activated derivative of arachidonic acid, designed for efficient covalent conjugation to primary amines. This compound is critical for researchers and manufacturers requiring stable, site-specific labeling of proteins, peptides, and other amine-containing biomolecules. It is primarily utilized in the life sciences sector for advanced biochemical research, assay development, and the production of diagnostic reagents.

Application

• Bioconjugation and Protein Labeling: Used to covalently attach arachidonic acid or its derivatives to antibodies, enzymes, and other proteins for functional studies and probe generation.
• Lipidomics Research: Serves as a key reagent for synthesizing standardized internal standards and labeled analogs for mass spectrometry-based lipid analysis.
• Biomarker Development: Facilitates the creation of conjugated antigens and haptens for immunoassay development targeting eicosanoid pathways.
• Signal Transduction Studies: Enables the direct modification of cellular proteins to investigate the role of lipid signaling in inflammation and other physiological processes.
• Diagnostic Reagent Synthesis: Employed in the manufacturing of specialized reagents for clinical diagnostic kits, particularly those related to inflammatory markers.
• Pharmaceutical Research: Used in drug discovery for creating drug-carrier conjugates or for studying drug-lipid interactions.

Basic Information

Product Name	Arachidonic Acid n-Hydroxysuccinimidyl Ester
CAS No.	187224-28-8
Molecular Formula	C24H35NO4
Molecular Weight	401.54 g/mol
Synonyms	AA-NHS; Arachidonic Acid NHS Ester; Arachidonoyl N-Hydroxysuccinimide Ester; N-Succinimidyl Arachidonate; 5Z,8Z,11Z,14Z-Eicosatetraenoyl N-Hydroxysuccinimide Ester; 5,8,11,14-Eicosatetraenoic Acid N-Hydroxysuccinimide Ester; Arachidonic Acid Active Ester; NSC 326330
EINECS	Contact for details

Quality Control

Every batch of our Arachidonic Acid n-Hydroxysuccinimidyl Ester is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive biochemical applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.