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L-α-Phosphatidyl-Ethanolamine Dipalmitoyl, n-Succinyl Sodium Salt CAS NO 186800-61-3


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CAS No.:186800-61-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

L-α-Phosphatidyl-Ethanolamine Dipalmitoyl, n-Succinyl Sodium Salt is a high-purity, chemically modified phospholipid derivative, specifically engineered for advanced research and formulation applications. This compound is valued for its unique amphiphilic properties and the introduction of a succinyl group, which enhances its utility in creating stable, functional lipid-based systems. It is an essential material for scientists and product developers in the pharmaceutical, biotechnology, and advanced material science sectors seeking to innovate in drug delivery, diagnostic imaging, and biomimetic membrane research.

Application

  • Liposomal Drug Delivery Systems: As a key functional excipient for constructing targeted and long-circulating liposomes, enhancing drug encapsulation and stability.
  • Biomimetic Membrane Research: Used in the creation of model membranes and vesicles for studying membrane protein interactions, fusion processes, and cellular signaling.
  • Diagnostic Agent Formulation: Serves as a stabilizing agent and carrier for contrast agents in medical imaging, such as MRI and ultrasound.
  • Bioconjugation & Surface Modification: The reactive succinyl group provides an anchor point for coupling targeting ligands, peptides, or fluorescent probes.
  • Cosmetic & Dermal Formulations: Employed in high-end skincare products as a bioactive lipid component to improve skin barrier function and delivery of active ingredients.
  • Biophysical Studies: Essential for calorimetry, spectroscopy, and microscopy studies investigating lipid bilayer properties and dynamics.

Basic Information

Product Name L-α-Phosphatidyl-Ethanolamine Dipalmitoyl, n-Succinyl Sodium Salt
CAS No. 186800-61-3
Molecular Formula C41H78NNaO11P
Molecular Weight 839.02 g/mol
Synonyms 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-succinyl sodium salt; DPPE-Succinyl Sodium Salt; Succinyl-DPPE Sodium Salt; N-Succinyl-1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine Sodium Salt; PE(16:0/16:0)-Succinyl Na; Phosphatidylethanolamine, N-succinyl derivative, sodium salt; Lipid anchor reagent; SDPPE
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Quality Control

Our L-α-Phosphatidyl-Ethanolamine Dipalmitoyl, n-Succinyl Sodium Salt is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and MS for identity verification, to ensure it meets the stringent requirements for research and formulation. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (NMR) Conforms to structure
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 95% (Area %)
Solubility Soluble in chloroform, methanol; forms micelles in aqueous buffer
Water Content (KF) ≤ 2.0 %
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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