Description

Australine Hydrochloride is a potent and specific glycosidase inhibitor derived from natural sources. This high-purity compound is critical for biochemical research and pharmaceutical development, particularly in the study of carbohydrate metabolism and related disorders. It is primarily utilized by research institutions and pharmaceutical companies engaged in metabolic disease research, antiviral studies, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a specific inhibitor in enzymatic studies to investigate glycosidase function and carbohydrate processing pathways.
• Pharmaceutical R&D: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of treatments for metabolic disorders like diabetes and lysosomal storage diseases.
• Antiviral Studies: Investigated for its potential to inhibit viral glycosidases, which are crucial for viral replication and infectivity.
• Cell Biology: Employed in cell culture studies to modulate glycosylation processes and study their effects on cell signaling and protein function.
• Standards & Calibration: Used as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical laboratories.

Basic Information

Product Name	Australine Hydrochloride
CAS No.	186766-07-4
Molecular Formula	C8H16ClNO4
Molecular Weight	225.67 g/mol
Synonyms	(1R,2R,3R,7S,7aR)-1,2,7-Trihydroxypyrrolizidine hydrochloride; (1R,2R,3R,7S,7aR)-1,2,7-Trihydroxyhexahydro-1H-pyrrolizine hydrochloride; Australine HCl; 1,2,7-Trihydroxypyrrolizidine hydrochloride; Pyrrolizidine alkaloid hydrochloride
EINECS	Contact for details

Quality Control

Our Australine Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.