Description

6,7,8-Indolizinetriol, Octahydro-1-Methoxy-, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)- is a complex, stereochemically defined indolizine derivative that serves as a valuable chiral building block and synthetic intermediate. Its precise stereochemistry and functional group array make it a critical compound for advanced pharmaceutical research and fine chemical synthesis. This high-purity specialty chemical is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for complex molecules targeting neurological or metabolic pathways.
• Asymmetric Synthesis: Used as a sophisticated chiral pool starting material or auxiliary for constructing stereocenters in total synthesis projects.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization due to its unique polyhydroxylated indolizine scaffold.
• Agrochemical Development: Acts as an intermediate for creating novel, biologically active compounds with potential herbicidal or insecticidal properties.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme mechanisms or biological pathways, leveraging its specific hydroxyl group pattern.
• Academic & Institutional Research: A valuable compound for methodological development in organic synthesis and catalysis within university and government laboratories.

Basic Information

Product Name	6,7,8-Indolizinetriol, Octahydro-1-Methoxy-, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)-
CAS No.	185899-47-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(1S,6R,7S,8R,8aR)-Octahydro-1-methoxy-6,7,8-indolizinetriol; 1S-(1α,6β,7α,8β,8aβ)-Octahydro-1-methoxy-6,7,8-indolizinetriol; 1-Methoxy-octahydro-6,7,8-indolizinetriol (1S-stereoisomer); (1S,6R,7S,8R,8aR)-1-Methoxyoctahydro-6,7,8-indolizinetriol; Indolizinetriol derivative 185899-47-2; CAS 185899-47-2
EINECS	Contact for details

Quality Control

Our 6,7,8-Indolizinetriol, Octahydro-1-Methoxy-, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis and impurity profiling, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing identity, purity (by HPLC), and specific tests are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere or in a desiccated environment at a controlled room temperature (15-25°C). Prolonged exposure to air or moisture should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.