Description

1,6,7,8-Indolizinetetrol, Octahydro-7-Methyl-, (1S,6S,7S,8R,8Ar)- is a high-purity, stereochemically defined indolizine derivative, identified by CAS number 185899-22-3. This compound is valued for its complex polyhydroxylated structure, which serves as a critical chiral building block and intermediate in advanced organic synthesis. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), natural product analogs, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents.
• Organic Synthesis Building Block: Used in the construction of complex natural product analogs and heterocyclic compounds due to its functionalized indolizine core.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in studies exploring new catalytic methodologies.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.
• Academic & Industrial R&D: A valuable material for fundamental research in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	1,6,7,8-Indolizinetetrol, Octahydro-7-Methyl-, (1S,6S,7S,8R,8Ar)-
CAS No.	185899-22-3
Molecular Formula	C9H17NO4
Molecular Weight	203.24 g/mol
Synonyms	(1S,6S,7S,8R,8aR)-Octahydro-7-methyl-1,6,7,8-indolizinetetrol; 7-Methyloctahydro-1,6,7,8-indolizinetetrol; (1S,6S,7S,8R,8aR)-7-Methyloctahydroindolizine-1,6,7,8-tetrol; Indolizine-1,6,7,8-tetrol derivative; Polyhydroxylated indolizidine analog; Chiral indolizinetetrol
EINECS	Contact for details

Quality Control

Every batch of 1,6,7,8-Indolizinetetrol, Octahydro-7-Methyl-, (1S,6S,7S,8R,8Ar)- is produced and controlled under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical and stereochemical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.