Description

(-)-2,6-Bis[2-[3As-(2(3'Ar*,8'As*),3A,8A)-3A,8A-Dihydro-8H-Indeno[1,2-D]Oxazole]]Pyridine is a sophisticated chiral ligand and building block of significant interest in advanced organic synthesis and catalysis. Its complex, rigid structure makes it a highly selective component for constructing novel molecular architectures. This compound is primarily sought by research and development teams in the pharmaceutical and fine chemical industries. It serves as a critical intermediate for developing new active pharmaceutical ingredients (APIs) and specialty catalysts.

Application

• Asymmetric Catalysis: A key chiral ligand for transition metal-catalyzed asymmetric reactions, including hydrogenation and cross-coupling.
• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of complex, optically active drug candidates and APIs.
• Material Science Research: Used in the development of novel chiral organic frameworks and functional materials with specific optical properties.
• Methodology Development: Employed by academic and industrial research groups to develop new synthetic methodologies and catalytic systems.
• Ligand Library Synthesis: A valuable component for creating diverse libraries of chiral ligands for high-throughput screening in catalyst discovery.

Basic Information

Product Name	(-)-2,6-Bis[2-[3As-(2(3'Ar*,8'As*),3A,8A)-3A,8A-Dihydro-8H-Indeno[1,2-D]Oxazole]]Pyridine
CAS No.	185346-09-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(-)-2,6-Bis(2-(3a,8a-dihydro-8H-indeno[1,2-d]oxazol-2-yl))pyridine; Pyridine, 2,6-bis[2-(3a,8a-dihydro-8H-indeno[1,2-d]oxazol-2-yl)]-, (3aS,3'aS,8aS,8'aS)-; Chiral Bis(oxazoline) Pyridine Ligand; BOX-Py Ligand Derivative; (3aS,3'aS,8aS,8'aS)-2,6-Bis(2-(3a,8a-dihydro-8H-indeno[1,2-d]oxazol-2-yl))pyridine
EINECS	Contact for details

Quality Control

Our production of this high-value chiral compound adheres to strict quality control protocols to ensure batch-to-batch consistency and purity for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques, including chiral HPLC and NMR spectroscopy, to confirm identity and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and analytical data is provided with every shipment to support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and handling properties. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.