Description

Cymal-4 is a high-purity, non-ionic detergent widely used in biochemistry and structural biology for the solubilization and stabilization of membrane proteins. Its critical value lies in its ability to maintain the native structure and function of sensitive proteins, enabling downstream analysis and research. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors who require reliable reagents for membrane protein studies. Cymal-4 CAS NO 181135-57-9 is a key tool for advancing drug discovery and understanding complex biological systems.

Application

• Solubilization of integral membrane proteins for purification and characterization.
• Stabilization of membrane protein complexes for structural biology techniques like X-ray crystallography and cryo-electron microscopy (cryo-EM).
• Preparation of lipid-protein nanodiscs and other membrane mimetic systems.
• Functional reconstitution of membrane proteins into liposomes or planar lipid bilayers.
• Use in buffer systems for the extraction of membrane-bound enzymes and receptors.
• Critical reagent in the study of G-protein-coupled receptors (GPCRs) and ion channels.
• Component of formulations for the storage and handling of delicate membrane protein samples.

Basic Information

Product Name	Cymal-4
CAS No.	181135-57-9
Molecular Formula	C10H20O5
Molecular Weight	220.26 g/mol
Synonyms	5-Cyclohexyl-1-pentyl-β-D-maltoside; Cyclohexylpentyl-β-D-maltoside; n-Pentyl-β-D-cyclohexylmaltoside; n-Pentyl-β-cyclohexylmaltoside; β-Cymal-4; Maltose neopentyl glycol (MNG) analog; Heptyl-β-cyclohexylmaltoside analog; Detergent for membrane proteins
EINECS	Contact for details

Quality Control

Our Cymal-4 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high performance in demanding applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and critical micelle concentration (CMC) verification, to meet the exacting standards of life science research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and key functional parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which can affect performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Critical Micelle Concentration (CMC)	0.15 - 0.25 mM (Typical in water)
pH (1% solution)	5.0 - 7.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.