Description

4-Methylumbelliferyl 2-Sulfamino-2-Deoxy-α-D-Glucopyranoside is a specialized fluorogenic substrate designed for the sensitive detection and quantification of specific enzymatic activity. This compound is critical for researchers and quality control laboratories requiring precise, high-throughput biochemical assays. It is primarily utilized in the life sciences, pharmaceutical development, and diagnostic reagent manufacturing sectors for enzyme kinetics and inhibitor screening studies.

Application

• Enzymatic Assay Substrate: A key fluorogenic substrate for the detection and kinetic analysis of sulfatase and glycosidase enzymes.
• Diagnostic Reagent Manufacturing: Used in the formulation of diagnostic kits for lysosomal storage disorders and other enzyme deficiency-related diseases.
• Pharmaceutical Research & HTS: Enables high-throughput screening (HTS) for drug discovery programs targeting specific sulfatase pathways.
• Biochemical Research: Essential tool for studying enzyme mechanisms, inhibition, and activity in cell lysates and purified protein preparations.
• Quality Control in Biologics: Employed in QC labs to monitor enzyme activity during the production and purification of therapeutic proteins.

Basic Information

Product Name	4-Methylumbelliferyl 2-Sulfamino-2-Deoxy-α-D-Glucopyranoside
CAS No.	180088-52-2
Molecular Formula	C₁₆H₁₉NO₁₁S
Molecular Weight	457.39 g/mol
Synonyms	4-MU-α-GlcNS; 4-Methylumbelliferyl α-D-N-sulfoglucosaminide; 4-Methylumbelliferyl 2-deoxy-2-sulfamido-α-D-glucopyranoside; α-GlcNS-4MU; 4-MU-α-GlcNS; Fluorogenic substrate for sulfamidase; N-sulfoglucosamine 4-methylumbelliferyl substrate
EINECS	Contact for details

Quality Control

Our 4-Methylumbelliferyl 2-Sulfamino-2-Deoxy-α-D-Glucopyranoside is produced under stringent quality management systems to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance in standard assay conditions. We support compliance with relevant GMP and ISO guidelines for raw materials used in diagnostic and pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Fluorogenic Activity	Conforms to functional assay
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.