Description

3-Oleoylestrone-2,4,16,16-D4 is a deuterated derivative of oleoylestrone, a fatty acid ester of the estrogenic steroid estrone. This compound is a high-purity, isotopically labeled standard of significant value for research and analytical applications, particularly in mass spectrometry. It is primarily utilized by scientists and quality control laboratories in the pharmaceutical, biotechnology, and academic research sectors. The deuterium labeling provides a crucial internal reference for precise quantitative analysis and metabolic studies.

Application

• Internal Standard for LC-MS/MS: Serves as a critical quantitative reference standard in liquid chromatography-tandem mass spectrometry for analyzing oleoylestrone and related metabolites.
• Metabolic Pathway Research: Used as a tracer to study the biosynthesis, distribution, and degradation pathways of steroid fatty acid esters in biological systems.
• Pharmaceutical R&D: Supports drug discovery and development efforts focused on estrogenic signaling and lipid metabolism, enabling accurate pharmacokinetic and bioanalytical assays.
• Clinical Diagnostics Development: Aids in the development and validation of sensitive diagnostic assays for hormonal and metabolic disorders.
• Biomarker Verification: Employed in the verification and absolute quantification of potential lipidomic biomarkers in research settings.
• Quality Control Reference: Acts as a certified reference material (CRM) to ensure the accuracy and precision of analytical methods within quality control laboratories.

Basic Information

Product Name	3-Oleoylestrone-2,4,16,16-D4
CAS No.	180003-17-2
Molecular Formula	C36H52D4O3
Molecular Weight	548.86 g/mol (approx.)
Synonyms	3-Oleoylestrone-d4; Estrone 3-oleate-2,4,16,16-d4; Oleoylestrone-d4; (8R,9S,13S,14S)-13-Methyl-2,4,16,16-tetradeuterio-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-3-yl (9Z)-octadec-9-enoate; Deuterated Oleoylestrone; 3-O-(9Z-Octadecenoyl)estrone-2,4,16,16-d4
EINECS	Contact for details

Quality Control

Every batch of 3-Oleoylestrone-2,4,16,16-D4 is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. Our products are supplied with a detailed Certificate of Analysis (COA) that includes data for identity, purity (by HPLC), isotopic enrichment, and other critical parameters. We ensure compliance with the rigorous standards required for research and analytical reference materials, supporting traceability and reproducibility in your work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Store in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Enrichment (D-content)	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.