Description

1,2-Didecanoyl-Sn-Glycero-3-Phosphate is a synthetic, enantiomerically pure phospholipid derivative, specifically a phosphatidic acid analogue with defined acyl chains. This compound serves as a critical high-purity biochemical building block and model membrane component for advanced research and development. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precisely defined lipid structures for liposome formulation, membrane biophysics studies, and synthetic biology applications.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: As a component for constructing model membranes or functionalized delivery vesicles for drug and gene delivery systems.
• Biochemical Research: As a substrate or standard in enzymatic assays studying phospholipase activity, lipid metabolism, and signal transduction pathways.
• Membrane Biophysics: Used to create defined lipid bilayers for studying membrane protein interactions, permeability, and fusion mechanisms.
• Synthetic Biology: As a building block for constructing artificial cells or minimal membrane systems with tailored properties.
• Pharmaceutical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in lipid-based drug product analysis.
• Advanced Material Science: Investigation into self-assembling nanostructures and bio-inspired materials for sensors and coatings.

Basic Information

Product Name	1,2-Didecanoyl-Sn-Glycero-3-Phosphate
CAS No.	178603-81-1
Molecular Formula	C23H45O8P
Molecular Weight	480.57 g/mol
Synonyms	1,2-Didecanoyl-sn-glycerol-3-phosphate; PA(10:0/10:0); Phosphatidic Acid(20:0); 1,2-Dicaprinoyl-sn-glycero-3-phosphate; Decanoic acid, 1-[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester, (2R)-; sn-Glycerol-3-phosphate 1,2-didecanoate; 3-sn-Phosphatidic acid di-C10:0; 1,2-Didecanoyl-rac-glycero-3-phosphate (racemic mixture)
EINECS	Contact for details

Quality Control

Our 1,2-Didecanoyl-Sn-Glycero-3-Phosphate is produced under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity, enantiomeric purity, and chemical composition. A comprehensive Certificate of Analysis (COA) detailing all specification parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Enantiomeric Purity (Chiral HPLC)	≥ 98% sn-1,2 isomer
Water Content (KF)	≤ 2.0 %
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.