Description

Carbamic Acid, [(1R,4S)-4-Hydroxy-2-Cyclopenten-1-Yl]-, 1,1-Dimethylethyl Ester is a high-purity, chiral building block of significant value in advanced organic synthesis. This compound is critical for the development of complex, biologically active molecules due to its defined stereochemistry and functionalized cyclopentene core. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, including nucleoside analogs and antiviral compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of nucleoside-based drugs and prodrugs.
• Antiviral Drug Research: Used in the development of novel antiviral compounds targeting specific enzymatic pathways.
• Asymmetric Synthesis: Serves as a versatile starting material for constructing complex molecules with defined stereocenters.
• Protease Inhibitor Development: Employed in the research and synthesis of potential protease inhibitors.
• Chemical Biology Probes: Utilized to create labeled or modified probes for studying biological mechanisms.
• Process Chemistry & Scale-up: Supports route development and optimization for the commercial production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Carbamic Acid, [(1R,4S)-4-Hydroxy-2-Cyclopenten-1-Yl]-, 1,1-Dimethylethyl Ester
CAS No.	178152-48-2
Molecular Formula	C10H17NO3
Molecular Weight	199.25 g/mol
Synonyms	(1R,4S)-4-[(tert-Butoxycarbonyl)amino]-2-cyclopenten-1-ol; (1R,4S)-4-[(tert-Butoxycarbonyl)amino]cyclopent-2-en-1-ol; tert-Butyl N-[(1R,4S)-4-hydroxycyclopent-2-en-1-yl]carbamate; Boc-4-Amino-2-cyclopenten-1-ol (cis); cis-4-[(tert-Butoxycarbonyl)amino]-2-cyclopenten-1-ol; (1R,4S)-4-(Boc-amino)-2-cyclopenten-1-ol; N-Boc-cis-4-amino-2-cyclopenten-1-ol
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(1R,4S)-4-Hydroxy-2-Cyclopenten-1-Yl]-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and pharmaceutical development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We support compliance with cGMP and ICH Q7 guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under a dry atmosphere to prevent decomposition. For long-term storage, consider storage under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.