Description

(1R)-1-(2-Methoxyphenyl)Butylamine CAS NO 177726-46-4 is a chiral amine building block of significant importance in asymmetric synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with high enantiomeric purity, which is critical for developing active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries engaged in advanced organic synthesis and process development.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalyst Ligand: Used in the development and synthesis of chiral ligands for transition metal catalysis to induce stereoselectivity in reactions.
• Agrochemical Synthesis: Serves as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Process R&D: Utilized in research laboratories for method development and studying stereoselective transformation pathways.

Basic Information

Product Name	(1R)-1-(2-Methoxyphenyl)Butylamine
CAS No.	177726-46-4
Molecular Formula	C11H17NO
Molecular Weight	179.26 g/mol
Synonyms	(R)-1-(2-Methoxyphenyl)butan-1-amine; (R)-1-(o-Methoxyphenyl)butylamine; (1R)-1-(2-Methoxyphenyl)-1-butanamine; (R)-(-)-1-(2-Methoxyphenyl)butylamine; (R)-o-Methoxy-α-ethylbenzylamine; (R)-1-(2-Methoxyphenyl)butylamine; (R)-2-Methoxy-α-ethylbenzenemethanamine
EINECS	Contact for details

Quality Control

Our (1R)-1-(2-Methoxyphenyl)Butylamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.