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3''-Sulphated Lewis X, Methyl Glycoside Sodium Salt (~90%) CAS NO 176166-23-7
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CAS No.:176166-23-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3''-Sulphated Lewis X, Methyl Glycoside Sodium Salt (~90%) is a well-defined, synthetic carbohydrate derivative, specifically a sulfated trisaccharide glycoside. This compound is a crucial biochemical tool for studying carbohydrate-protein interactions, particularly those involving selectins and other sulfated glycan-binding proteins. It is primarily utilized by researchers and developers in the fields of glycobiology, immunology, and pharmaceutical discovery for use as a reference standard, enzyme substrate, or inhibitor in assay development.
Application
- Glycobiology Research: As a critical reference standard and probe for investigating sulfated glycan-mediated cell adhesion and signaling pathways.
- Enzyme Assay Development: Serving as a specific substrate or inhibitor for sulfotransferases, glycosidases, and lectins (e.g., selectins).
- Pharmaceutical Screening: Used in high-throughput screening (HTS) campaigns to identify novel anti-inflammatory or anti-metastatic drug candidates that target selectin-carbohydrate interactions.
- Diagnostic Reagent Component: Potential use in the development of diagnostic kits for diseases where sulfated Lewis X antigens are biomarkers.
- Bioconjugation & Probe Synthesis: Acts as a building block for the synthesis of more complex neoglycoconjugates, biotinylated probes, or microarray elements.
- Standards for Analytical Chemistry: Providing a qualified standard for HPLC, MS, or NMR analysis in quality control of related biopharmaceuticals.
Basic Information
| Product Name | 3''-Sulphated Lewis X, Methyl Glycoside Sodium Salt (~90%) |
| CAS No. | 176166-23-7 |
| Molecular Formula | Contact for details |
| Molecular Weight | Contact for details |
| Synonyms | 3'-Sulfated Lewis X Methyl Glycoside Sodium Salt; 3'-Sulfo Lewis X Methyl Glycoside; Sodium (2S,3R,4S,5R,6R)-6-[(2R,3S,4R,5R,6S)-4,5-Dihydroxy-2-(hydroxymethyl)-6-[(2R,3S,4R,5R)-4,5,6-trihydroxy-3-(sulfooxy)-2-(hydroxymethyl)oxan-2-yl]oxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate; Sulphated Lex Methyl Glycoside; 3'-SO3-LeX-OMe Na+; Sulfated Lewis X Trisaccharide Methyl Glycoside |
| EINECS | Contact for details |
Quality Control
Every batch of 3''-Sulphated Lewis X, Methyl Glycoside Sodium Salt is produced and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your research and regulatory needs.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (NMR) | Conforms to structure |
| Identification (MS) | Conforms to structure |
| Purity (HPLC) | ≥ 90% |
| Water Content (KF) | ≤ 5.0% |
| Heavy Metals | < 20 ppm |
| Bacterial Endotoxins | < 1.0 EU/mg (if applicable) |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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