Description

(S)-A-Hydroxy-3-Furanacetonitrile is a high-value chiral intermediate characterized by its furan ring and nitrile functionality. This compound matters for its role as a critical building block in the synthesis of complex, biologically active molecules, offering precise stereochemical control. It is primarily needed by pharmaceutical and agrochemical R&D teams for developing new active ingredients, as well as by fine chemical manufacturers producing advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in antiviral and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry is required for efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis.
• Fine Chemical Production: Employed in multi-step organic synthesis to introduce the furan-acetonitrile moiety into more complex molecular architectures.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(S)-A-Hydroxy-3-Furanacetonitrile
CAS No.	174754-57-5
Molecular Formula	C7H7NO2
Molecular Weight	137.14 g/mol
Synonyms	(S)-2-Hydroxy-2-(furan-3-yl)acetonitrile; (S)-α-Hydroxy-3-furanacetonitrile; (S)-3-Furylglycolonitrile; (S)-Hydroxy(3-furyl)acetonitrile; (S)-2-(3-Furyl)-2-hydroxyacetonitrile; (S)-3-Furyl(hydroxy)acetonitrile; (S)-Furan-3-ylglycolonitrile
EINECS	Contact for details

Quality Control

Our (S)-A-Hydroxy-3-Furanacetonitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) for assay and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.