Description

Octadecyl-2-Acetamido-2-Deoxy-β-D-Glucopyranoside is a high-purity, non-ionic glycolipid surfactant derived from N-acetylglucosamine, featuring a long C18 alkyl chain. This compound is critically important for its ability to solubilize and stabilize membrane proteins without denaturation, making it indispensable for structural biology and biophysical research. It is primarily needed by pharmaceutical R&D teams, biochemical researchers, and manufacturers of diagnostic reagents for applications in protein purification, crystallization, and assay development.

Application

• Membrane Protein Solubilization & Purification: A key detergent for extracting and maintaining the native conformation of integral membrane proteins for structural studies.
• Biophysical Research & Crystallography: Used to create stable, homogeneous protein-detergent complexes suitable for X-ray crystallography and NMR analysis.
• Diagnostic Reagent Formulation: Serves as a stabilizing agent in immunoassay buffers and diagnostic kits to enhance shelf-life and performance.
• Liposome & Nanoparticle Preparation: Acts as a component in the formulation of lipid-based drug delivery systems and model membranes.
• Cell Biology & Biochemistry: Employed in cell lysis buffers and for reconstituting functional membrane proteins into artificial lipid bilayers.
• Pharmaceutical Development: Utilized in early-stage drug discovery processes targeting membrane-bound receptors and enzymes.

Basic Information

Product Name	Octadecyl-2-Acetamido-2-Deoxy-β-D-Glucopyranoside
CAS No.	173725-29-6
Molecular Formula	C28H55NO7
Molecular Weight	517.74 g/mol
Synonyms	N-Octadecyl-β-D-glucopyranosylamine N-acetate; Octadecyl-β-D-N-acetylglucosaminide; C18-NAG; n-Octadecyl 2-acetamido-2-deoxy-β-D-glucopyranoside; 2-Acetamido-2-deoxy-1-O-octadecyl-β-D-glucopyranose; β-D-GlcNAc-OC18; N-Acetyl-D-glucosamine, 1-O-octadecyl-; Glycolipid detergent C18
EINECS	Contact for details

Quality Control

Our Octadecyl-2-Acetamido-2-Deoxy-β-D-Glucopyranoside is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade specifications. Custom purity grades, including >98% and >99%, are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.