Description

Dnp-Arg-Pro-Leu-Ala-Leu-Trp-Arg-Ser-Oh is a synthetic, nonapeptide derivative featuring a dinitrophenyl (Dnp) protecting group, which is critical for research in peptide chemistry and enzymology. This compound is primarily valued as a specialized substrate or inhibitor for studying protease activity, particularly in the context of substrate specificity and enzyme kinetics. It serves as an essential research tool for biochemists, pharmaceutical developers, and academic institutions focused on proteolytic pathways, drug discovery, and biochemical assay development.

Application

• Protease/Enzyme Research: Used as a chromogenic or fluorogenic substrate to investigate the catalytic mechanism and specificity of serine or other proteases.
• Biochemical Assay Development: Employed in the design and validation of high-throughput screening (HTS) assays for identifying potential enzyme inhibitors.
• Pharmaceutical R&D: Serves as a key intermediate or reference standard in the discovery and development of novel therapeutic agents targeting proteases.
• Academic Studies: Utilized in university and research institute laboratories for fundamental studies on peptide hydrolysis and enzyme kinetics.
• Diagnostic Reagent Component: Can be incorporated into diagnostic kits for detecting specific enzymatic activity in clinical or research samples.

Basic Information

Product Name	Dnp-Arg-Pro-Leu-Ala-Leu-Trp-Arg-Ser-Oh
CAS No.	172666-82-9
Molecular Formula	C58H86N18O13
Molecular Weight	1219.4 g/mol
Synonyms	Dnp-Arg-Pro-Leu-Ala-Leu-Trp-Arg-Ser-OH; Dnp-R-P-L-A-L-W-R-S-OH; N-2,4-Dinitrophenylarginylprolylleucylalanylleucyltryptophylarginylserine; Dnp Nonapeptide; Protease Substrate Peptide; Chromogenic Peptide Substrate; 172666-82-9; Dnp-Arg-Pro-Leu-Ala-Leu-Trp-Arg-Ser
EINECS	Contact for details

Quality Control

Every batch of Dnp-Arg-Pro-Leu-Ala-Leu-Trp-Arg-Ser-Oh is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. We adhere to high-purity standards suitable for research applications, with comprehensive characterization via HPLC, MS, and NMR. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and meet your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccant or under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Assay	≥ 97%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.