Description

Palmatine Chloride Hydrate is a quaternary isoquinoline alkaloid salt, widely recognized for its significant biological and pharmacological activity. This high-purity compound is essential for research and development in life sciences, serving as a critical reference standard and active ingredient. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of nutraceuticals and traditional medicine products seeking standardized bioactive components.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and quality control of related pharmaceutical products and herbal extracts in analytical laboratories.
• Biochemical Research: Serves as a key tool compound for studying cellular pathways, enzyme inhibition, and its interactions with biological targets in vitro.
• Natural Product & Nutraceutical Formulation: Incorporated into standardized herbal supplements and wellness products for its purported bioactive properties.
• Academic Research: Employed in universities and research institutes for pharmacological studies, including investigations into anti-inflammatory, antimicrobial, and metabolic effects.
• Chemical Synthesis Intermediate: Acts as a building block or precursor for the semi-synthesis of more complex alkaloid derivatives and novel chemical entities.

Basic Information

Product Name	Palmatine Chloride Hydrate
CAS No.	171869-95-7
Molecular Formula	C21H22ClNO4 · xH2O
Molecular Weight	389.86 (Anhydrous basis)
Synonyms	Palmatine HCl Hydrate; 2,3,9,10-Tetramethoxyprotoberberinium Chloride Hydrate; Berberine, 5,6-dihydro-9,10-dimethoxy-; NSC 364471; 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium Chloride Hydrate; Columbamine Chloride Hydrate (related isomer); Natural Yellow 18 (related to salt form)
EINECS	Contact for details

Quality Control

Our Palmatine Chloride Hydrate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets high-grade standards for research use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange-yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.