Description

(3A,5B,7A,12A)-3,7,12,19-Tetrahydroxy-Cholan-24-Oic Acid is a high-purity, polyhydroxylated bile acid derivative, a key intermediate in advanced pharmaceutical synthesis and biochemical research. This compound is valued for its specific stereochemistry and functional groups, which are critical for developing targeted therapeutic agents and conducting precise metabolic studies. It is primarily sought by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors for applications requiring high chemical fidelity and reliable supply.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel therapeutic agents, particularly in metabolic and liver disease research.
• Biochemical Research: Used as a reference standard and reagent in studies of bile acid metabolism, receptor binding, and enzymatic pathways.
• Fine Chemical Synthesis: Serves as a chiral precursor for the production of complex, stereospecific molecules in advanced organic chemistry.
• Reference Material: Employed in analytical laboratories for method development, calibration, and quality control of related compounds.
• Metabolite Standard: Essential for quantitative analysis in bioanalytical assays, pharmacokinetic studies, and diagnostic test development.

Basic Information

Product Name	(3A,5B,7A,12A)-3,7,12,19-Tetrahydroxy-Cholan-24-Oic Acid
CAS No.	171524-64-4
Molecular Formula	C24H40O6
Molecular Weight	424.57 g/mol
Synonyms	3α,7α,12α,19-Tetrahydroxy-5β-cholan-24-oic Acid; 19-Hydroxychenodeoxycholic Acid; 3α,7α,12α,19-Tetrahydroxy-5β-cholanoic Acid; Tetrahydroxy Cholanoic Acid; 19-OH-CDCA; (3α,5β,7α,12α)-3,7,12,19-Tetrahydroxycholan-24-oic Acid
EINECS	Contact for details

Quality Control

Our (3A,5B,7A,12A)-3,7,12,19-Tetrahydroxy-Cholan-24-Oic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards suitable for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.