Description

Tezacitabine is a synthetic nucleoside analog with significant research and development applications in the pharmaceutical sector. This compound is valued for its potential as a key intermediate or active pharmaceutical ingredient (API) in the development of novel antiviral and anticancer therapeutics. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions engaged in drug discovery and preclinical studies.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of novel nucleoside-based drug candidates.
• Antiviral Agent Development: Investigated for its potential activity against viral targets, making it valuable for antiviral drug discovery programs.
• Oncology Research: Studied for its mechanism of action and efficacy as a potential chemotherapeutic agent in cancer research.
• Biochemical Studies: Used as a reference standard or probe in enzymatic and metabolic pathway studies.
• Preclinical Formulation: Employed in the development and testing of dosage forms during preclinical stages of drug development.

Basic Information

Product Name	Tezacitabine
CAS No.	171233-40-2
Molecular Formula	C9H12FN3O4
Molecular Weight	245.21 g/mol
Synonyms	4-Amino-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 2'-Deoxy-2',2'-difluorocytidine; Gemcitabine Impurity; DFDC; LY-188011; 1-(2-Deoxy-2,2-difluoro-D-erythro-pentofuranosyl)cytosine
EINECS	Contact for details

Quality Control

Our Tezacitabine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.